Figure 3. Phenotypic features of patients. A: A 4-year-old boy (III:1) with left hand scar at thenar prominence at the site of previous surgery to excise of duplication of thumb. B: A 6-month-old girl (III:2) has no signs of limb malformations. C: A 36-year-old woman (II:2) with residual signs of a previous extra left thumb , and left thenar hypoplasia and hypoplasia of thumb. D: A 60-year-old man (I:1) with residual incomplete excision of an extra right thumb.