Table 5 of
Cheng, Mol Vis 2013; 19:955-969. Table 5 of
Cheng, Mol Vis 2013; 19:955-969.
Table 5. Comparison of Molecular Functions Associated with Up-Regulated and Down-Regulated Molecules (DAVID).
| GO Term: Molecular Function | Count | % | P-value |
|---|---|---|---|
| Upregulated Molecules: | |||
| Protein dimerization activity | 24 | 5.27 | 8.05E-07 |
| Protein binding | 162 | 35.60 | 6.10E-06 |
| Transcription factor activity | 35 | 7.69 | 3.71E-05 |
| Chemokine activity | 7 | 1.54 | 1.25E-04 |
| Transcription regulator activity | 44 | 9.67 | 3.84E-04 |
| G-protein-coupled receptor binding | 8 | 1.76 | 6.34E-04 |
| Sequence-specific DNA binding | 23 | 5.05 | 3.27E-03 |
| Rac guanyl-nucleotide exchange factor activity | 3 | 0.66 | 4.18E-03 |
| Non-membrane spanning protein tyrosine kinase activity | 5 | 1.10 | 9.47E-03 |
| Amine transmembrane transporter activity | 6 | 1.32 | 1.01E-02 |
| Cytokine activity | 10 | 2.20 | 1.35E-02 |
| Cyclin-dependent protein kinase regulator activity | 3 | 0.66 | 3.82E-02 |
| Downregulated Molecules: | |||
| Photoreceptor activity | 3 | 1.04 | 6.85E-03 |
| Cation binding | 53 | 18.40 | 3.20E-02 |
| Ion binding | 53 | 18.40 | 3.96E-02 |
| Metal ion binding | 52 | 18.06 | 4.03E-02 |
| Phosphoric ester hydrolase activity | 8 | 2.78 | 4.76E-02 |
| Inositol or phosphatidylinositol kinase activity | 3 | 1.04 | 5.27E-02 |