Table 4 of
Cheng, Mol Vis 2013; 19:955-969. Table 4 of
Cheng, Mol Vis 2013; 19:955-969.
Table 4. Comparison of Biologic Processes Associated with the Up-Regulated and Down-Regulated Molecules.
| GO Term: Biologic Processes | Count | % | P-value |
|---|---|---|---|
| Upregulated Molecules: | |||
| Immune system process | 55 | 12.09 | 2.96E-14 |
| Inflammatory response | 29 | 6.37 | 6.15E-14 |
| Defense response | 39 | 8.57 | 4.52E-13 |
| Complement activation, classical pathway | 8 | 1.76 | 2.71E-06 |
| Cytokine-mediated signaling pathway | 10 | 2.20 | 2.82E-06 |
| Regulation of programmed cell death | 29 | 6.37 | 3.29E-05 |
| Regulation of vesicle-mediated transport | 10 | 2.20 | 7.34E-05 |
| Phagocytosis | 8 | 1.76 | 8.06E-05 |
| Protein processing | 10 | 2.20 | 1.38E-04 |
| Regulation of protein kinase cascade | 11 | 2.42 | 1.98E-03 |
| Intracellular signaling cascade | 33 | 7.25 | 4.84E-03 |
| Regulation of catalytic activity | 20 | 4.40 | 5.58E-03 |
| Cation homeostasis | 11 | 2.42 | 6.71E-03 |
| Regulation of localization | 18 | 3.96 | 7.21E-03 |
| Downregulated Molecules: | |||
| Visual perception | 10 | 3.47 | 1.99E-06 |
| Phototransduction | 5 | 1.74 | 1.38E-04 |
| Glycerolipid metabolic process | 8 | 2.78 | 6.35E-04 |
| Eye photoreceptor cell differentiation | 4 | 1.39 | 2.10E-03 |
| Detection of abiotic stimulus | 5 | 1.74 | 2.75E-03 |
| Detection of external stimulus | 5 | 1.74 | 4.62E-03 |
| Phosphoinositide metabolic process | 5 | 1.74 | 5.50E-03 |
| Phospholipid metabolic process | 7 | 2.43 | 1.03E-02 |
| Response to radiation | 6 | 2.08 | 2.28E-02 |
| Actin filament organization | 4 | 1.39 | 2.51E-02 |
| Glycerolipid biosynthetic process | 4 | 1.39 | 2.75E-02 |
| Metabolic process | 92 | 31.94 | 3.35E-02 |
| Neuron development | 8 | 2.78 | 4.72E-02 |
| Lipid metabolic process | 14 | 4.86 | 5.05E-02 |