Table 3 of
Cheng, Mol Vis 2013; 19:955-969. Table 3 of
Cheng, Mol Vis 2013; 19:955-969.
Table 3. Top Canonical Pathways Affected in the rd3 Retina.
| Top Canonical Pathways | Molecules |
|---|---|
| Phototransduction | GNB3, GNAT1, PDC, OPN5, RGR, GUCA1B, GUCY2F, OPN1SW |
| Glycerophospholipid Metabolism | HMOX1, GPD1, CDS1, PNPLA3, AGPAT2, PLA2R1, ENPP2, PLCH2, PLA2G7 |
| TNFR1 Signaling | JUN, PAK6, CRADD, TNFRSF1A, TNFAIP3, XIAP |
| Acute Phase Response Signaling | HMOX1, SERPING1, JUN, C3, TF, TNFRSF1A, CP, SERPINA3, OSMR, STAT3 |
| Signaling by Rho Family GTPases | ROCK2, JUN, GNB3, GNAT1, PAK6, ARPC1B, VIM, GFAP, PARD3, ACTA1, MSN |
| Endothelin-1 Signaling | HMOX1, JUN, GNAT1, PNPLA3, PLA2R1, GUCY2F, PLCH2, PLA2G7, OPN1SW |
| Complement System | SERPING1, C3, CFI, C1QA |
| Phospholipid Degradation | HMOX1, PNPLA3, PLA2R1, ENPP2, PLCH2, PLA2G7 |
| Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes | HMOX1, RAC2, ARPC1B, HCK, FGR, ACTA1 |
| Aryl Hydrocarbon Receptor Signaling | TGM2, NCOA7, JUN, CDKN1A, ALDH1L1, NCOA3, AHR |