Table 3 of Chen, Mol Vis 2013; 19:944-954.

Table 3. Association of Complement factor H SNPs with early ARM

SNP Genotype Frequency Association
Control ARM OR P
N % N % (95% CI)
rs3753394 TT 49 31.2 51 32.3 1.04 0.868
TC 74 47.1 68 43 0.76 - 1.42
CC 34 21.7 39 24.7
T 172 54.8 170 53.8
C 142 45.2 146 46.2
rs800292 GG 51 32.5 55 34.8 1.08 0.680
GA 79 50.3 66 41.8 0.79 - 1.48
AA 27 17.2 37 23.4
G 181 57.6 176 55.7
A 133 42.4 140 44.3
rs1061170 CC 144 91.7 146 92.4 0.91 0.987
CT 13 8.3 12 7.6 0.4 - 2.07
TT 0 0 0 0
C 301 95.9 304 96.2
T 13 4.1 12 3.8
rs2274700 CC 49 31.2 48 30.4 1.17 0.372
CT 84 53.5 75 47.5 0.85 - 1.6
TT 24 15.3 35 22.2
C 182 58 171 54.1
T 132 42 145 45.9
rs3753396 GG 39 24.8 42 26.6 1.09 0.632
AG 83 52.9 71 44.9 0.8 - 1.49
AA 35 22.3 45 28.5
G 161 51.3 155 49.1
A 153 48.7 161 50.9
rs1065489 TT 39 24.8 41 25.9 1.08 0.690
GT 82 52.2 73 46.2 0.79 - 1.48
GG 36 22.9 44 27.8
T 160 51 155 49.1
G 154 49 161 50.9

The ORs of the minor alleles were calculated using the additive model controlling both sex and age. SNP: single nucleotide polymorphism; ARM: age-related maculopathy; OR: odds ratio; CI: confidence interval.

Chen, Mol Vis 2013; 19:944-954. http://www.molvis.org/molvis/v19/944

©2013 Molecular Vision http://www.molvis.org/molvis/

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