Figure 1 of Chen, Mol Vis 2013; 19:944-954.


Figure 1. Linkage disequilibrium of age-related maculopathy susceptibility protein 2/HtrA serine peptidase 1 and complement factor H single nucleotide polymorphisms. A: The single nucleotide polymorphisms (SNPs) rs10490924, rs11200638, and rs2672598 in age-related maculopathy susceptibility protein 2/HtrA serine peptidase 1 (ARMS2/HTRA1) form a haplotype block in a 6 kb genomic region. (B) The SNPs rs10490924, rs11200638, and rs2672598 in complement factor H (CFH) form a long haplotype block in a 26 kb genomic region according to the criteria of the confidence intervals, an algorithm proposed by Gabriel et al. [20]. The solid line with an arrow indicates the transcription direction.