Figure 1. Capture of amyloid deposits from the cornea with lattice corneal dystrophy (LCD) type 1 variant by laser capture microdissection. Polymorphic amyloid deposits from a cornea with an LCD type 1 variant caused by the A546D mutation in the transforming growth factor beta induced (TGFBI) gene (A) were procured from tissue sections with laser capture microdissection (B). A: Prominent foci of amyloid were observed in formalin-fixed paraplast-embedded tissue sections of the grafted LCD type 1 variant cornea. B: Clearly defined amyloid deposits were easily procured from tissue sections and used for the proteomic analyses.