Table 3 of Kaur, Mol Vis 2013; 19:822-828.


Table 3. Major haplotype frequencies at the three loci harboring the ARMS2 (A69S and del443ins54) and HTRA1 variants in the Indian and Australian cohorts

HAPLOTYPES (5’-3’) SOUTH INDIAN COHORT (n=433) AUSTRALIAN COHORT (n=1054)
rs1094924 (ARMS2) del443ins54 (ARMS2) rs11200638 (HTRA1) % Cases
(N=227) % Controls (N=206) P values OR (95%CI) % Cases (N=624) % Controls (N=430) P values OR (95%CI)
T Indel A 57.8 30.3 5.70x10-16 3.16 (2.34-4.19) 44.1 20 6.33x10-30 3.15 (2.57-3.85)
G Wt* G 33 55.6 2.35x10-11 0.39 (0.29-0.52) 55.3 79.8 1.02x10-30 0.31 (0.25-0.38)
G - G 35.8 59.5 4.49x10-12 0.38 (0.29-0.50) 55.4 79.8 1.43x10-30 0.31 (0.26-0.38)
T - A 58.4 30.4 1.82x10-16 3.20 (2.42-4.25) 44.1 20.2 1.55x10-29 3.11 (2.55-3.81)
T Indel - 59.1 31.8 1.32x10-15 3.09 (2.34-4.10) 44.4 20 1.18x10-30 3.19 (2.61-3.91)
G Wt* - 33.5 50.4 2.54x10-13 0.36 (0.27-0.47) 55.4 79.8 1.43x10-30 0.31 (0.26-0.38)
- Indel A 50.8 31.8 2.41x10-15 3.06 (2.31-4.05) 44.1 20 6.33x10-30 3.15 (2.57-3.86)
- Wt* G 35.5 59.1 5.04x10-12 0.38 (0.29-0.50) 55.3 79.8 1.02x10-30 0.31 (0.26-0.38)