Table 2 of
Kaur, Mol Vis 2013; 19:822-828. Table 2 of
Kaur, Mol Vis 2013; 19:822-828.
Table 2. Genotype counts of the ARMS2 and HTRA1 SNPs in the Indian and Australian cohorts
| Population | SNP (gene) | Genotypes | Genotype counts | P value | Odds ratios (95% CI) | |
|---|---|---|---|---|---|---|
| Cases | Controls | |||||
| Australian | rs10490924 (ARMS2) | GG | 189 | 271 | - | Ref |
| GT | 282 | 138 | <0.0001 | 2.93 (2.22 - 3.86) | ||
| TT | 145 | 16 | <0.0001 | 12.99 (7.51 - 22.49) | ||
| Indel -EU427539 (ARMS2) | Wt/Wt | 190 | 269 | - | Ref | |
| Wt/Indel | 306 | 137 | <0.0001 | 3.16 (2.41 - 4.16) | ||
| Indel/Indel | 119 | 15 | <0.0001 | 11.23 (6.36 – 19.82) | ||
| rs11200638 (HTRA1) | GG | 194 | 271 | - | Ref | |
| GA | 292 | 138 | <0.0001 | 2.96 (2.25 – 3.89) | ||
| AA | 130 | 17 | <0.0001 | 10.68 (6.24 – 18.29) | ||
| Indian | rs10490924 (ARMS2) | GG | 39 | 85 | - | Ref |
| GT | 84 | 94 | 0.004 | 1.95 (1.21 – 3.15) | ||
| TT | 99 | 26 | <0.0001 | 8.30 (4.67 – 14.74) | ||
| Indel -EU427539 (ARMS2) | Wt/Wt | 44 | 84 | - | Ref | |
| Wt/Indel | 79 | 88 | 0.017 | 1.71 (1.16 – 2.75) | ||
| Indel/Indel | 104 | 34 | <0.0001 | 5.84 (3.43 – 9.94) | ||
| rs11200638 (HTRA1) | GG | 44 | 61 | - | Ref | |
| GA | 70 | 67 | 0.01 | 1.45 (0.87 – 2.42) | ||
| AA | 84 | 17 | <0.0001 | 6.85 (3.58 – 13.12) | ||