Figure 1. MMP2 levels in the serum from early AMD (n=75), nAMD (n=89), PCV (n=98), and control subjects (n=80) were measured with ELISA. One-way ANOVA with a post-hoc Scheffe test demonstrated that the serum concentration of MMP2 in the PCV group was significantly higher than that of the control (p=0.001), nAMD (p=0.005), and early AMD groups (p<0.001). Abbreviations: AMD=Age-related macular degeneration; nAMD=neovascular Age-related macular degeneration; PCV=Polypoidal choroidal vasculopathy; ELISA=Enzyme-linked immunosorbent assay.