Figure 1. Intraocular pressure in mouse eyes over the course of 4 months. Data were obtained using the TonoLab under isoflurane anesthesia and represented as the mean intraocular pressure (IOP) in mm Hg. Error bars indicate the standard error of the mean (SEM). Transforming growth factor beta (TGFβ) transgenic (TG) mice, matrix metalloproteinase-9 knockout (MMP-9KO)/TGFβ1 transgenic mice, and MMP-9KO mice all exhibited elevated IOP compared to wild-type (WT) mice at all three time points examined. *** p<0.001; ** p<0.01 * p<0.05 (compared to WT).