Table 2 of
Cénit, Mol Vis 2013; 19:638-643. Table 2 of
Cénit, Mol Vis 2013; 19:638-643.
Table 2. Allelic and genotype frequencies of PTPN22 genetic variants in overall uveitis patients, uveitis patients stratified according to the anatomic classification and healthy controls from Spanish population.
| SNP | Subgroup (n) | GG | GA | AA | MAF (%) | Allelic P -value | OR (95% CI) |
|---|---|---|---|---|---|---|---|
| rs2476601 | Controls (n=721) | 628 (87.10) | 89 (12.34) | 4 (0.55) | 110 (6.75) | ||
| Uveitis (n=215) | 186 (86.51) | 28 (13.02) | 1 (0.47) | 30 (6.98) | 0.86 | 1.04 (0.68–1.59) | |
| IU (n=37) | 30 (81.08) | 7 (19.92) | 0 (0.00) | 7 (9.46) | 0.36 | 1.45 (0.65–3.24) | |
| PU (n=104) | 88 (84.62) | 16 (15.38) | 0 (0.00) | 16 (7.69) | 0.61 | 1.16 (0.67–2.00) | |
| PAN (n=56) | 52 (92.86) | 3 (5.36) | 1 (1.78) | 5 (4.46) | 0.35 | 0.65 (0.26–1.63) |
| SNP | Subgroup (n) | CC | CT | TT | MAF (%) | Allelic P -value | OR (95% CI) |
|---|---|---|---|---|---|---|---|
| rs33996649 | Controls (n=718) | 668 (93.04) | 49 (6.82) | 1 (0.14) | 51 (3.55) | ||
| Uveitis (n=217) | 202 (93.09) | 15 (6.91) | 0 (0.00) | 15 (3.46) | 0.92 | 0.97 (0.54–1.75) | |
| IU (n=38) | 37 (97.37) | 1 (2.63) | 0 (0.00) | 1 (1.31) | 0.3 | 0.36 (0.05–2.66) | |
| PU (n=104) | 95 (91.35) | 9 (8.65) | 0 (0.00) | 9 (4.33) | 0.58 | 1.23 (0.60–2.53) | |
| PAN (n=56) | 52 (92.86) | 4 (7.14) | 0 (0.00) | 4 (3.57) | 0.99 | 1.01 (0.36–2.84) |