Table 3 of
Ren, Mol Vis 2013; 19:561-574. Table 3 of
Ren, Mol Vis 2013; 19:561-574.
Table 3. BMI-1 expression and clinicopathological features of retinoblastomas.
| Grading of % BMI-1 positive cells | |||||
|---|---|---|---|---|---|
| *0 | 1 | 2 | 3 | 4 | |
| (A) Rb differentiation | |||||
| 1. Undifferentiated (n=24) | 1 | 5 | 5 | 7 | 6 |
| 2. Differentiated (n=10) | 0 | 3 | 7 | 0 | 0 |
| p=0.05 (Mann–Whitney U test) | |||||
| (B) Rb retinas | |||||
| 1. Undifferentiated Rb (n=17) | 3 | 6 | 8 | 0 | 0 |
| 2. Differentiated Rb (n=10) | 1 | 5 | 4 | 0 | 0 |
| p=0.86 (Mann–Whitney U test) | |||||
| (B1) Outer nuclear layer | |||||
| 1. Undifferentiated Rb (n=17) | 3 | 6 | 8 | 0 | 0 |
| 2. Differentiated Rb (n=10) | 1 | 6 | 3 | 0 | 0 |
| p=0.49 (Mann–Whitney U test) | |||||
| (B2) Inner nuclear layer | |||||
| 1. Undifferentiated Rb (n=17) | 3 | 4 | 7 | 3 | 0 |
| 2. Differentiated Rb (n=10) | 1 | 2 | 5 | 1 | 0 |
| p=0.24 (Mann–Whitney U test) | |||||
| (C) Tumor invasion | |||||
| 1. No invasion (n=9) | 2 | 4 | 2 | 1 | 0 |
| 2. Invasion (n=25) | 1 | 3 | 9 | 6 | 6 |
| (i) to optic nerve only (n=14) | 0 | 2 | 7 | 3 | 2 |
| (ii) to choroid only (n=3) | 1 | 1 | 1 | 0 | 0 |
| (iii) to both (n=8) | 0 | 0 | 1 | 3 | 4 |
| (D) Optic nerve invasion (n=22) | |||||
| 1. To optic nerve head (n=13) | 0 | 2 | 7 | 4 | 0 |
| 2. Past lamina cribrosa (n=9) | 0 | 0 | 1 | 3 | 6 |