Figure 1. Viability effect of curcumin on ARPE-19 cells at different concentrations and time points. A: Dose effect of curcumin on cells treated with different concentrations of curcumin for 6 h. Curcumin at concentrations 1–20
μM did not affect the viability of the ARPE-19 cells. B: Time effect of curcumin on cells treated with 20 μM curcumin at different time points. Cells treated with curcumin (20 μM)
for 15 h and 20 h induced cell death, compared with the control. Cell survival was determined with CellTiter-Blue assay (absorbance
at 560/590 nm). Data represent mean±SEM from five separate samples. *p<0.05 versus control, **p<0.001 versus control.