Table 3 of
Xin, Mol Vis 2013; 19:526-535. Table 3 of
Xin, Mol Vis 2013; 19:526-535.
Table 3. Meta-analysis for the association between TNF-α −857C/T, −863C/A, and −238G/A polymorphisms and the risks of open angle glaucoma
| Contrast | Number of studies | OR | 95%CI | M a | I2(%) | P valueb |
|---|---|---|---|---|---|---|
| -857C/T (rs1799724) | ||||||
| T versus C | 5 | 1.055 | 0.831–1.216 | F | 0.0 | 0.798 |
| TT versus CC | 5 | 1.261 | 0.659–2.14 | F | 0.0 | 0.694 |
| CT versus CC | 5 | 0.967 | 0.775–1.206 | F | 0.0 | 0.548 |
| TT/CT versus CC | 5 | 0.984 | 0.794–1.219 | F | 0.0 | 0.705 |
| -863C/A (rs645836) | ||||||
| A versus C | 3 | 0.928 | 0.636–1.353 | R | 70.3 | 0.035 |
| AA versus CC | 3 | 1.855 | 0.273–12.623 | R | 75.0 | 0.018 |
| AC versus CC | 3 | 0.844 | 0.660–1.078 | F | 0.0 | 0.375 |
| AA/AC versus CC | 3 | 0.871 | 0.618–1.227 | F | 52.1 | 0.124 |
| -238G/A (rs361525)c | ||||||
| A versus G | 3 | 1.088 | 0.696–1.941 | F | 34.7 | 0.216 |
| AA/GA versus GG | 3 | 1.076 | 0.681–1.701 | F | 31.7 | 0.232 |