Table 1 of Xin, Mol Vis 2013; 19:526-535.

Table 1. Characteristics of individual studies for associations between TNF-α polymorphisms and risks of open angle glaucoma

Authors Year Country Type Gender Agea Genotypes distribution PHWEc
Case b control b
11 12 22 11 12 22
-308G/A (rs1800629)
Bozkurt 2012 Turkey HTG 40.7/38.3 65.1/66.2 66 19 1 171 21 1 0.686
Al-Dabbagh 2011 Saudi Arabia HTG 47/50 58/55 59 68 8 110 76 14 0.860
Fan 2010 China HTG 65.5/59.7 62.8/69.8 226 25 1 167 29 5 0.012
Fan 2010 China NTG 54/59.7 63.2/69.8 87 12 0 167 29 5 0.012
Fan 2010 China HTG/NTG 66/59.7 21.3/69.8 37 9 0 167 29 5 0.012
Razeghinejad 2009 Iran HTG na na 57 13 0 190 10 0 0.717
Razeghinejad 2009 Iran EXG na na 48 10 1 190 10 0 0.717
Mossbock 2009 Austria EXG 42.2/- 76.1/75.3 152 48 4 151 51 2 0.305
Khan 2009 Pakistan EXG 67/64 45.3/44.2 53 39 30 110 13 3 0.004
Tekeli 2008 Turkey EXG 55.5/51.8 66.0/64.2 103 7 0 92 18 0 0.350
Mossbock 2006 Austria HTG 42.1/42.1 72.3/72.7 79 35 0 161 61 6 0.938
Funayama 2004 Japan HTG 56.7/42.2 65.1/70.6 192 2 0 212 6 0 0.836
Funayama 2004 Japan NTG 44.7/42.2 60.3/70.6 211 6 0 212 6 0 0.836
Lin 2003 China HTG 50/53.4 55/50 28 13 19 66 30 7 0177
-857C/T (rs1799724)
Fan 2010 China HTG 65.5/59.7 62.8/69.8 189 58 5 159 39 3 0.732
Fan 2010 China NTG 54/59.7 63.2/69.8 80 19 0 159 39 3 0.732
Fan 2010 China HTG/NTG 66/59.7 21.3/69.8 35 11 0 159 39 3 0.732
Funayama 2004 Japan HTG 56.7/42.2 65.1/70.6 135 49 10 144 69 5 0.324
Funayama 2004 Japan NTG 44.7/42.2 60.3/70.6 148 64 5 144 69 5 0.324
-863C/A (rs645836)
Wang 2012 China HTG 52/53 67/67 148 70 16 120 84 26 0.062
Funayama 2004 Japan HTG 56.7/42.2 65.1/70.6 141 46 7 161 56 1 0.093
Funayama 2004 Japan NTG 44.7/42.2 60.3/70.6 159 55 3 161 56 1 0.093
-238G/A (rs361525)
Bozkurt 2012 Turkey HTG 40.7/38.3 65.1/66.2 79 7 0 180 13 0 0.628
Mossbock 2009 Austria EXG 42.2/- 76.1/75.3 182 21 1 189 15 0 0.586
Mossbock 2006 Austria HTG 42.1/42.1 72.3/72.7 107 7 0 205 23 0 0.423

a the mean age of case and control; b 1 represent the common allele, while 2 represents the minor allele. cp for Hardy–Weinberg equilibrium test in controls; “na“ means that the data were not available; Abbreviations: HTG, high-tension glaucoma; NTG, normal-tension glaucoma; EXG, exfoliative glaucoma.

Xin, Mol Vis 2013; 19:526-535. http://www.molvis.org/molvis/v19/526

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