Table 4 of
Micheal, Mol Vis 2013; 19:441-xxx.
Table 4. MMP-9 SNP genotype frequencies in POAG and PACG patients and unaffected controls
Controls n=118 (%) | POAG n=112 (%) | p (χ2) | p (χ2) | OR (95% CI) | PACG n=82 (%) | p (χ2) | p (χ2) | OR (95% CI) | |
---|---|---|---|---|---|---|---|---|---|
MMP-9 = c.-1562C>T | |||||||||
CC | 74(62.7) | 70 (62.5) | 0.24 (2.85) | Reference | 56(68.3) | 0.23 (2.93) | Reference | ||
CT | 37(31.3) | 40(35.7) | 0.22 (0.63) | 1.14 (0.63-2.06) | 25(30.5) | 0.71 (0.13) | 0.89 (0.46-1.73) | ||
TT | 7(6) | 2(1.8) | 0.12 (2.37) | 0.30 (0.04-1.67) | 1(1.2) | 0.08 (2.91) | 0.19 (0.01-0.60) | ||
MMP-9 = c.836A>G | |||||||||
AA | 40 (33.9) | 26(23.2) | 0.05 (5.75) | Reference | 15(18.3) | <0.001 (12.13) | Reference | ||
AG | 53(44.9) | 48(42.9) | 0.30 (1.07) | 1.39 (0.71-2.75) | 32(39.0) | 0.20 (1.61) | 1.61 (0.72-3.60) | ||
GG | 25(21.2) | 38(33.9) | 0.01 (5.64) | 2.34 (1.09-5.05) | 35(42.7) | <0.001 (11.27) | 3.73 (1.59-8.86) |