Table 2 of Micheal, Mol Vis 2013; 19:441-xxx.


Table 2. MMP-1 and MMP-7 SNP genotype frequencies in POAG and PACG patients and unaffected controls

Controlsn=118 (%) POAGn=112 (%) p (χ2) p (χ2) OR (95% CI) PACG
n=82 (%) p (χ2) p (χ2) OR (95% CI)
MMP-1= c.-1607-1606insGG
1G/1G 53(44.9) 27(24) 0.001 (13.04) Reference 25(30.5) 0.09 (4.75) Reference
1G/2G 45(38.1) 49(44) 0.01 (5.93) 2.14 (1.10-4.15) 36(43.9) 0.10 (2.58) 1.70 (0.85-3.41)
2G/2G 20(17.0) 36(32) <0.001 (12.35) 3.53 (1.63-7.73) 21(25.6) 0.04 (4.16) 2.23 (0.96-5.21)
MMP-7 = c.-181T>C
TT 43(36.4) 36(32.1) 0.35 (2.07) Reference 24(29.3) 0.55 (1.18) Reference
TC 57(48.3) 64(57.1) 0.31 (1.03) 1.34 (0.73-2.47) 43(52.4) 0.35 (0.86) 1.35 (0.68-2.69)
CC 18(15.3) 12(10.8) 0.60 (0.27) 0.80 (0.31-2.03) 15(18.3) 0.35 (0.86) 1.49 (0.59-3.80)