Table 2 of
Micheal, Mol Vis 2013; 19:441-xxx. Table 2 of
Micheal, Mol Vis 2013; 19:441-xxx.
Table 2. MMP-1 and MMP-7 SNP genotype frequencies in POAG and PACG patients and unaffected controls
| Controls n=118 (%) | POAG n=112 (%) | p (χ2) | p (χ2) | OR (95% CI) | PACG n=82 (%) | p (χ2) | p (χ2) | OR (95% CI) | |
|---|---|---|---|---|---|---|---|---|---|
| MMP-1= c.-1607-1606insGG | |||||||||
| 1G/1G | 53(44.9) | 27(24) | 0.001 (13.04) | Reference | 25(30.5) | 0.09 (4.75) | Reference | ||
| 1G/2G | 45(38.1) | 49(44) | 0.01 (5.93) | 2.14 (1.10-4.15) | 36(43.9) | 0.10 (2.58) | 1.70 (0.85-3.41) | ||
| 2G/2G | 20(17.0) | 36(32) | <0.001 (12.35) | 3.53 (1.63-7.73) | 21(25.6) | 0.04 (4.16) | 2.23 (0.96-5.21) | ||
| MMP-7 = c.-181T>C | |||||||||
| TT | 43(36.4) | 36(32.1) | 0.35 (2.07) | Reference | 24(29.3) | 0.55 (1.18) | Reference | ||
| TC | 57(48.3) | 64(57.1) | 0.31 (1.03) | 1.34 (0.73-2.47) | 43(52.4) | 0.35 (0.86) | 1.35 (0.68-2.69) | ||
| CC | 18(15.3) | 12(10.8) | 0.60 (0.27) | 0.80 (0.31-2.03) | 15(18.3) | 0.35 (0.86) | 1.49 (0.59-3.80) | ||