Figure 3. Positions of putative disease-associated mutations in latent transforming growth factor-beta binding protein 2. Positions of disease-associated mutations observed here are shown above the schematic representation of the latent transforming growth factor-beta binding protein 2 (LTBP2) structure, and the positions of the mutations previously reported are presented below the diagram. Diseases associated with the mutations are also given. Symbols used for the various LTBP2 domains are indicated; horizontal lines represent protein regions not known to be specific domains.