Figure 6. Expression levels of several genes required for normal depolarizing bipolar cell (DBC) function in several mouse lines. Note that expression of Gpr179 was decreased 370-fold in the tg21 no b-wave (nob) mice and in Gpr179^nob5 mutant mice. Other depolarizing bipolar cell (DBC) genes were expressed at normal or slightly higher than normal levels in the tg21 nob and Gpr179^nob5 mice. Values were normalized to control measures and actin served as the internal standard. Values are expressed as mean±SD (n=3).