Figure 7. The status of CP49 does not affect ephrin-A5^-/- cataract formation. A-D: Ephrin-A5^+/+ lenses with the CP49 mutation (Ephrin-A5^+/+;CP49^-/-) appear transparent (A, lens is denoted by dotted line), while ephrin-A5^-/- lenses, regardless of the status of CP49, display cataract formation (B-D). Lens deformations were observed in 100% of the ephrin-A5^-/-;CP49^+/+ lenses (n=4), 73% of the ephrin-A5^-/-;CP49^+/- lenses (n=11), and 83% of the ephrin-A5^-/-;CP49^-/- lenses (n=6).