Figure 3. Variants in the zinc finger E-box binding homeobox 1 (
ZEB1, also known as
TCF8) gene on chromosome 10p11.22 that have been detected in patients with Fuchs endothelial corneal dystrophy (FECD). The gene
is drawn from 5′ to 3′ reflecting its physical orientation on the forward strand of the reference genome. Drawn as described
in the caption for
Figure 1, with the red font indicating variants identified in our African American FECD cases and variants marked with an asterisk
(*) indicating newly identified variants in African Americans with FECD that have not been previously reported in patients
with FECD.