Table 6 of
Whitmore, Mol Vis 2013; 19:2274-2297. Table 6 of
Whitmore, Mol Vis 2013; 19:2274-2297.
Table 6. Differentially expressed genes high-risk CFH genotypes (YH/HH) versus low-risk CFH genotype (YY).
| Ensembl ID | Symbol | Mean AMD | Mean Control | Fold change | Raw p value | FDR adj. P value | Name |
|---|---|---|---|---|---|---|---|
| ENSG00000127083 | OMD | 7.19 | 5.97 | 2.33 | 0.0047 | 0.8828 | osteomodulin |
| ENSG00000146374 | RSPO3 | 8.03 | 6.88 | 2.21 | 0.0058 | 0.8828 | R-spondin 3 |
| ENSG00000011465 | DCN | 8.86 | 7.72 | 2.19 | 0.0008 | 0.6616 | decorin |
| ENSG00000090104 | RGS1 | 8.10 | 7.10 | 2.00 | 0.0076 | 0.8828 | regulator of G-protein signaling 1 |
| ENSG00000186439 | TRDN | 8.04 | 7.08 | 1.95 | 0.0068 | 0.8828 | triadin |
| ENSG00000176971 | FIBIN | 8.87 | 7.98 | 1.86 | 0.0004 | 0.6215 | fin bud initiation factor homolog (zebrafish) |
| ENSG00000146233 | CYP39A1 | 7.31 | 6.46 | 1.80 | 0.0065 | 0.8828 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| ENSG00000196344 | ADH7 | 7.66 | 6.94 | 1.65 | 0.0017 | 0.7811 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| ENSG00000182230 | FAM153B | 7.23 | 6.54 | 1.61 | 0.0056 | 0.8828 | family with sequence similarity 153, member B |
| ENSG00000116667 | C1orf21 | 10.29 | 9.65 | 1.56 | 0.0000 | 0.1533 | chromosome 1 open reading frame 21 |
| ENSG00000121769 | FABP3 | 7.48 | 6.85 | 1.55 | 0.0088 | 0.8828 | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) |
| ENSG00000071189 | SNX13 | 8.46 | 7.82 | 1.55 | 0.0020 | 0.7811 | sorting nexin 13 |
| ENSG00000115607 | IL18RAP | 7.46 | 8.05 | −1.50 | 0.0083 | 0.8828 | interleukin 18 receptor accessory protein |
| ENSG00000089157 | RPLP0 | 7.00 | 7.59 | −1.51 | 0.0029 | 0.7833 | ribosomal protein, large, P0 |
| ENSG00000177076 | ACER2 | 6.82 | 7.41 | −1.51 | 0.0027 | 0.7833 | alkaline ceramidase 2 |
| ENSG00000146592 | CREB5 | 6.66 | 7.26 | −1.51 | 0.0070 | 0.8828 | cAMP responsive element binding protein 5 |
| ENSG00000182853 | VMO1 | 6.58 | 7.18 | −1.52 | 0.0051 | 0.8828 | vitelline membrane outer layer 1 homolog (chicken) |
| ENSG00000141753 | IGFBP4 | 9.07 | 9.71 | −1.56 | 0.0082 | 0.8828 | insulin-like growth factor binding protein 4 |
| ENSG00000167772 | ANGPTL4 | 7.66 | 8.32 | −1.58 | 0.0003 | 0.6215 | angiopoietin-like 4 |
| ENSG00000198959 | TGM2 | 8.87 | 9.61 | −1.68 | 0.0006 | 0.6616 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) |
| ENSG00000104332 | SFRP1 | 6.96 | 7.77 | −1.76 | 0.0067 | 0.8828 | secreted frizzled-related protein 1 |
| ENSG00000113083 | LOX | 6.29 | 7.14 | −1.80 | 0.0055 | 0.8828 | lysyl oxidase |
| ENSG00000167236 | CCL23 | 7.10 | 8.00 | −1.86 | 0.0066 | 0.8828 | chemokine (C-C motif) ligand 23 |
| ENSG00000068366 | ACSL4 | 7.33 | 8.33 | −2.00 | 0.0028 | 0.7833 | acyl-CoA synthetase long-chain family member 4 |
| ENSG00000138135 | CH25H | 6.20 | 7.21 | −2.01 | 0.0057 | 0.8828 | cholesterol 25-hydroxylase |
| ENSG00000102265 | TIMP1 | 10.09 | 11.11 | −2.03 | 0.0035 | 0.8828 | TIMP metallopeptidase inhibitor 1 |
| ENSG00000156804 | FBXO32 | 6.83 | 7.96 | −2.19 | 0.0000 | 0.1533 | F-box protein 32 |
| ENSG00000179431 | FJX1 | 8.10 | 9.28 | −2.27 | 0.0008 | 0.6616 | four jointed box 1 (Drosophila) |
| ENSG00000163638 | ADAMTS9 | 5.74 | 7.12 | −2.61 | 0.0008 | 0.6616 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
| ENSG00000124102 | PI3 | 6.40 | 7.79 | −2.63 | 0.0006 | 0.6616 | peptidase inhibitor 3, skin-derived |
| ENSG00000205362 | MT1A | 8.34 | 9.75 | −2.66 | 0.0082 | 0.8828 | metallothionein 1A |
| ENSG00000159167 | STC1 | 9.09 | 10.62 | −2.90 | 0.0027 | 0.7833 | stanniocalcin 1 |
| ENSG00000064886 | CHI3L2 | 6.20 | 7.83 | −3.10 | 0.0070 | 0.8828 | chitinase 3-like 2 |
| ENSG00000162992 | NEUROD1 | 5.41 | 7.30 | −3.69 | 0.0092 | 0.8828 | neurogenic differentiation 1 |
| ENSG00000115602 | IL1RL1 | 5.35 | 7.33 | −3.93 | 0.0001 | 0.3640 | interleukin 1 receptor-like 1 |