Figure 3. The effect of glucose oxidase on extracellular signal-related kinase 1/2 phosphorylation. Phosphoextracellular signal-related kinase 1/2 (ERK1/2) expression (upper panel) and total ERK1/2 (lower panel) in (A) lens epithelial cells (LECs) and (B) retinal pigment epithelial (RPE) cells treated with 0.25 mU/ml glucose oxidase in the presence or absence of 10 μM U-0126 for 24 h.