Figure 4. Dopamine and 3,4-dihydroxyphenylacetic acid levels in wild-type, rd1, and rd10 retinas with normal visual experience. A: 3,4-dihydroxyphenylacetic acid (DOPAC) levels were significantly lower in the rd1 and rd10 retinas compared to the wild-type (WT) retinas (analysis of variance [ANOVA] F_(2,43)=70.37, p<0.001). B: The dopamine levels were significantly higher in the rd10 retinas compared to the WT or rd1 retinas (ANOVA F_(2,43)=11.72, p<0.001). C: The DOPAC/dopamine (DA) ratio was significantly lower in the rd1 and rd10 retinas compared to the WT retinas (F_(2,43)=88.47, p<0.001; WT, n=19; rd1, n=12; rd10, n=13). Each bar represents the standard error of the mean (SEM). Post-hoc analysis: **p<0.001.