Table 2 of Guo, Mol Vis 2013; 19:2050-2057.

Table 2. The TOMM40rs2075650 genotype and allele frequency distribution and the results of association tests.

Frequency Distribution nAMD versus Control PCV versus Control
Parameters nAMD PCV Control P† OR(95%CI)‡ Power§ P† OR(95%CI)‡ Power§
Genotype AA 251(83.7) 244(81.3) 250(83.3) 1 - 845 -
GA 47(15.7) 54(18.0) 48(16.0)
GG 2(0.7) 2(0.7) 2(0.7)
Allele A 549(91.5) 542(90.3) 548(91.3) 0.918 0.979(0.654,1.466) 0.051 0.548 1.128(0.761,1.670) 0.080
G 51(8.5) 58(9.7) 52(8.7)
Dominant* AA 251(83.7) 244(81.3) 250(83.3) 0.912 0.976(0.634,1.502) 0.052 0.521 1.148(0.754,1.747) 0.098
GA+GG 49(16.3) 56(18.7) 50(16.7)
Recessive** AA+GA 298(99.3) 298(99.3) 298(99.3) 1 1.000(0.140, 7.146) - 1 1.000(0.140, 7.146) -
GG 2(0.7) 2(0.7) 2(0.7)

* The dominant model compared a combination of heterozygotes and rare homozygotes to the common homozygotes. ** The recessive model compared the rare homozygotes to a combination of common homozygotes and heterozygotes. † p<0.05 was considered significant. ‡ OR, odds ratio; CI, confidence interval. § Statistical power for detecting the association.

Guo, Mol Vis 2013; 19:2050-2057. http://www.molvis.org/molvis/v19/2050

©2013 Molecular Vision http://www.molvis.org/molvis/

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