Figure 6. Regression lines and values for all four mouse strains. Histogram of collagen fibril diameter density (fibers/um²) is plotted for the control mouse sclera (green line) and the glaucoma sclera (blue line) for each mouse strain. The ratio of the glaucoma density to control density at each diameter grouping is represented as a linear regression (red line) for each of the four mouse strains as follows: A: B6 (n=5, R²=0.01); B: CD1 (n=5, R²=0.08); C: Aca23-WT (n=5, R²=0.36), and D: Aca23 (n=5, R²=0.82). The Aca23 and CD1 glaucoma groups had a higher proportion of smaller collagen fibrils and a lower proportion of larger fibrils compared to their controls (both p<0.0001).