Molecular Vision: Aljohani, Mol Vis 2013; 19:1966-1984. Table 5

Table 5. Common ceramide species between control and glaucomatous aqueous humor.

Lipid Species*	m/z**	Control			Glaucoma
Lipid Species*	m/z**	Average normalized lipid amount	Standard error of mean	Donor frequency	Average normalized lipid amount	Standard error of mean	Fold Change	Donor frequency
Cer(d16:1/17:0)	524.5	3.82	2.71	10	0.18	0.09	0.05	8
Cer(d16:1/22:0)	597.4	1.90	0.64	2	0.59	0.23	0.31	2
Cer(d18:0/13:0)	497.9	10.78	8.32	10	0.19	0.06	0.02	6
Cer(d18:0/14:0)	515.7	4.14	1.83	2	0.18	0.04	0.04	4
Cer(d18:0/16:0)	540.6	4.81	2.13	2	0.16	0.03	0.03	3
Cer(d18:0/17:0)	550.6	5.71	4.68	8	0.19	0.09	0.03	9
Cer(d18:0/h17:0)	571.0	1.38	0.81	6	0.13	0.04	0.09	9
Cer(d18:0/h24:0)	670.6	2.33	0.93	7	0.09	0.02	0.04	4
Cer(d18:1/22:0)	625.9	0.22	0.10	2	0.16		0.71	1
Cer(d18:1/26:0)	675.3	0.38		1	0.16	0.05	0.42	4
Cer(d18:2/14:0)	508.5	11.52	8.85	10	0.16	0.05	0.01	10
Cer(d18:2/16:0)	533.9	31.74	36.42	10	0.15	0.05	0.005	9
Cer(d18:2/20:0)	594.9	32.88	20.17	4	0.12	0.04	0.004	2
Cer(d18:2/21:0)	606.1	14.94	10.91	10	0.15	0.06	0.01	9
Cer(d18:2/23:0)	633.5	0.70	0.25	9	0.17	0.04	0.24	7
Cer(t18:0/26:0)†	698.5	35.86	13.87	2	1.37	1.07	0.04	7
CerP(d18:0/16:0)	619.4	13.42	14.10	10	0.17	0.03	0.01	7
CerP(d18:1/12:0)	559.3	1.53	0.63	4	0.47	0.12	0.31	3
CerP(d18:1/14:0)	591.7	24.89	18.32	10	0.23	0.11	0.01	9
CerP(d18:1/24:1(15Z))	730.3	9.17	6.39	8	0.29	0.16	0.03	8
Ins-1-P-Cer(d18:1/22:0)	866.4	52.98	40.45	8	0.29	0.07	0.01	8
SM(d16:1/22:1)	760.1	33.85	26.51	10	0.26	0.14	0.01	9
SM(d16:1/24:0)	790.3	0.03	0.01	3	0.28	0.12	9.67	6
SM(d16:1/24:1)	789.5	1.46	0.17	3	0.23	0.00	0.16	1
SM(d17:1/22:0)	775.9	30.11	13.34	2	0.09	0.02	0.00	2
SM(d17:1/24:1)	802.5	12.70	10.52	9	0.23	0.06	0.02	9
SM(d18:0/12:0)	652.7	0.85	0.35	3	0.20	0.06	0.24	2
SM(d18:0/13:0)	664.4	43.74	32.97	7	0.18	0.07	0.00	10
SM(d18:0/15:0)†	694.1	3.37	0.72	2	0.26	0.15	0.08	4
SM(d18:0/17:0)	723.1	0.61	0.23	2	0.33	0.09	0.55	6
SM(d18:0/18:0)	737.6	0.01		1	0.13	0.05	50.87	2
SM(d18:0/20:0)	763.8	1.04		1	0.53		0.51	1
SM(d18:0/24:0)	821.1	3.04	1.57	3	0.16	0.06	0.05	3
SM(d18:0/26:0)	848.8	0.66	0.00	1	0.06	0.00	0.09	2
SM(d18:0/26:1(17Z))	847.4	1.53	0.40	3	0.65	0.16	0.43	2
SM(d18:1/12:0)	643.2	32.37	28.27	8	0.08	0.04	0.00	8
SM(d18:1/14:0)	678.9	4.67	1.51	3	0.14	0.02	0.03	3
SM(d18:1/15:0)	692.3	27.15	17.37	5	0.09	0.01	0.003	2
SM(d18:1/16:1)	701.2	1.52	0.54	5	0.19	0.05	0.12	4
SM(d18:1/17:0)	720.0	10.70	7.31	9	0.24	0.16	0.02	9
SM(d18:1/20:0)	763.3	182.77	81.70	2	0.18	0.06	0.001	3
SM(d18:1/24:0)	819.6	119.53	65.45	3	0.09		0.001	1
SM(d18:1/24:1(15Z))	815.6	5.34	5.07	8	0.23	0.08	0.04	9
SM(d18:1/26:1(17Z))	843.5	25.95	23.72	10	0.43	0.20	0.02	6
SM(d18:2/14:0)	673.9	39.85	32.14	6	0.30	0.11	0.01	4
SM(d18:2/15:0)	689.0	1.64	0.91	6	0.19	0.04	0.11	5
SM(d18:2/21:0)	770.3	2.99	1.71	6	0.48	0.35	0.16	9
SM(d18:2/22:1)	778.6	29.44	28.76	10	0.30	0.10	0.01	8
SM(d18:2/25:0)	831.2	12.36	10.57	7	0.58	0.22	0.05	7
SM(d19:1/18:0)	747.5	45.59	31.72	8	0.23	0.08	0.01	8

*The lipid species identification is based on Lipidmaps database, used as a *.csv file for bioinformatic analyses with MZmine 2.9 program. ** A representative mass/charge ratio is presented (variations in m/z was reconciled by MZmine 2.9). Average standard non-normalized dataset is presented here. For some lipid species identified, standard deviation value could not be calculated due to lack of presence in all samples. Average normalized lipid amount is pmol lipid per species/µg protein. Fold change is the ratio relative to control.† Cer(t18:0/26:0) and SM(d18:0/15:0) were found to have statistically significant difference between control and glaucoma using two tailed t-test (P≤0.05)