Table 4 of Guadarrama-Vallejo, Mol Vis 2013; 19:1937-1944.

Table 4. rs41435250 allelic and genotypic association testing results in a subgroup of 51 XFS/XFG patients who were negative for the TT risk genotype at rs2165241 and 130 controls.

rs41435250 Patients
(n=51) Controls
(n=130) OR (95% CI) P
Allele
T 31 (30.0) 21 (8.1) 4.9 (2.7 – 9.1) 5E-08
G 71 (70.0) 239 (91.9) 0.2 (0.1 – 0.4) 5E-08
Genotype
TT 4 (7.8) 2 (1.5) 5.5 (0.9 – 32.1)* 0.06
GT 23 (45.1) 17 (13.1) 5.1 (2.4 – 11.0)* 0.0001
GG 24 (47.1) 111 (85.4) 0.2 (0.08 – 0.3)* 0.00001

A marked increased risk associated to the rs41435250 T allele was observed. Abbreviations: n=number of subjects; OR=odds ratio; CI=confidence interval. *Adjusted by gender and age.

Guadarrama-Vallejo, Mol Vis 2013; 19:1937-1944. http://www.molvis.org/molvis/v19/1937

©2013 Molecular Vision http://www.molvis.org/molvis/

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