Table 1 of Goldstein, Mol Vis 2013; 19:1871-1884.

Table 1. Peak Genome-wide Association Results.

# Chromosome SNP Base position Size (Mb) of homozygous block observed in affected dogs and location (bp)
1 4 BICF2P1179952 14,140,022 Not observed
2 13 BICF2P1417808 37,566,130 0.16 (37,480,062–37,641,454)
3 BICF2S23534826 38,102,290 0.24 (38,057,700–38,300,049)
4 BICF2P802958 38,149,473
5 BICF2G630659956 39,187,805 0.93 (39,172,713–40,101,896)
6 BICF2G630659916 39,220,108
7 BICF2S23222210 42,456,241 0.045 (42,415,530–42,460,613)
8 BICF2P1192547 44,870,466 0.17 (44,818,724–44,987,699)
9 25 BICF2G630105512 47,523,118 2.09 (46,893,645–48,980,899)
10 BICF2P320510 47,531,764
11 BICF2P1326525 48,454,294
12 BICF2P1326531 48,455,885

Genome-wide association analysis of CanineHD Illumina SNP array data for 6 PRA-affected Basenji dogs and 3 controls, identified 12 SNPs sharing the highest -log10P-value of 4.6558. The SNP in CFA4 was not within a homozygous block. Seven SNPs in CFA13 were within three different homozygous blocks, each smaller than 1 Mb. Four SNPs in CFA25 were within a single 2.09 Mb homozygous block.

Goldstein, Mol Vis 2013; 19:1871-1884. http://www.molvis.org/molvis/v19/1871

©2013 Molecular Vision http://www.molvis.org/molvis/

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