Table 2 of Okumus, Mol Vis 2013; 19:1852-1858.

Table 2. Distributions of genotypes and alleles for the TRPM1, TRPM2, TRPM3, TRPM4, and TRPM5 gene polymorphisms between the case and control groups.

Gene Genotypes/ Alleles Controls n* Cases with POAG n* P value
SNP
TRPM1 CC/CT/TT 112/60/10 182 119/47/13 179 0.3399
rs28441327 C/T 284/80 285/73 0.6667
TRPM1 GG/GA/AA 112/60/10 182 117/51/10 178 0.6721
rs11070811 G/A 284/80 285/71 0.5627
TRPM1 AA/AG/GG 107/62/13 182 104/61/14 179 0.969
rs2241493 (Ser32Asn) A/G 276/88 269/89 0.8987
TRPM2 TT/TG/GG 97/72/11 180 95/73/11 179 0.9876
rs1618355 T/G 266/94 263/95 0.9644
TRPM2 CC/CT/TT 180/1/0 182 178/0/0 178 0.4987
rs9978351 (Arg1189=) C/T 362/2 356/0 0.4994
TRPM3 TT/TC/CC 181/1/0 182 179/0/0 179 1
rs113652718 (Val104Ala) T/C 363/1 358/0 1
TRPM3 CC/CA/AA 132/44/6 182 128/42/9 179 0.7106
rs1328142 C/A 308/56 298/60 0.6879
TRPM4 CC/CT/TT 85/73/24 182 93/67/18 178 0.4893
rs3760663 C/T 243/121 253/103 0.2427
TRPM4 GG/GA/AA 178/4/0 182 165/10/0 175 0.1055
rs71352737 (Trp525Ter) G/A 360/4 340/10 0.1088
TRPM5 CC/CT/TT 151/30/0 181 143/33/3 179 0.1874
rs34364959 (Gly900Ser) C/T 332/30 319/39 0.2885
TRPM5 CC/CT/TT 55/84/42 181 55/90/31 176 0.4076
rs4929982 (Arg578Gln) C/T 194/168 200/152 0.4286
TRPM5 CC/CT/TT 20/106/16 142 10/102/41 153 0.0009
rs34551253 (Ala456Thr) C/T 146/138 122/184 0.0063
TRPM5 AA/AG/GG 65/87/30 182 68/82/28 178 0.8869
rs886277 (Asn235Ser) A/G 214/147 218/138 0.7126
TRPM5 GG/GA/AA 100/67/15 182 96/68/12 176 0.8513
rs3986599 (Val254Ala) G/A 267/97 260/92 0.9437

*Numbers do not always add up to total numbers because of missing values on the BioMark dynamic array system. SNP, single nucleotide polymorphism. POAG, primary open-angle glaucoma.

Okumus, Mol Vis 2013; 19:1852-1858. http://www.molvis.org/molvis/v19/1852

©2013 Molecular Vision http://www.molvis.org/molvis/

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