Molecular Vision: Zhao, Mol Vis 2013; 19:1815-1825. Table 2

Table 2. The results of Kyoto Encyclopedia Genes and Genomes (KEGG) Pathway assay.

PathwayID	Definition	Fisher-P value	Enrichment Score
mmu04724	Glutamatergic synapse	0.00031325	3.504109
mmu05200	Pathways in cancer	0.000364143	3.438728
mmu04360	Axon guidance	0.000371743	3.429757
mmu04070	Phosphatidylinositol signaling system	0.001969461	2.705653
mmu00562	Inositol phosphate metabolism	0.002646183	2.57738
mmu04666	Fc gamma R-mediated phagocytosis	0.004516641	2.345184
mmu05100	Bacterial invasion of epithelial cells	0.006824978	2.165899
mmu04722	Neurotrophin signaling pathway	0.006869456	2.163078
mmu04350	TGF-beta signaling pathway	0.01427558	1.845406
mmu05014	Amyotrophic lateral sclerosis (ALS)	0.01455702	1.836928
mmu04510	Focal adhesion	0.0197738	1.70391
mmu04721	Synaptic vesicle cycle	0.02158243	1.6659
mmu04141	Protein processing in endoplasmic reticulum	0.02556368	1.592377
mmu04530	Tight junction	0.02830684	1.548109
mmu04810	Regulation of actin cytoskeleton	0.03108982	1.507382
mmu05212	Pancreatic cancer	0.03178773	1.497741
mmu05211	Renal cell carcinoma	0.03323187	1.478445
mmu04725	Cholinergic synapse	0.04785029	1.320115
mmu00564	Glycerophospholipid metabolism	0.04976589	1.303068
mmu00190	Oxidative phosphorylation	0.02234092	1.650899

Kyoto Encyclopedia Genes and Genomes (KEGG) pathway analysis was performed to identify possible enrichment of genes with specific biologic themes on the basis of identify possible enrichment of genes with specific biologic themes on the basis of biologic process, cellular component, and molecular function. We identified the significant KEGG pathways using the DAVID Bioinformatics Resources. Fisher’s exact test was used to determine the enrichment in categories with target genes in the DAVID bioinformatics resource.