Table 1 of
Boulling, Mol Vis 2013; 19:1779-1794. Table 1 of
Boulling, Mol Vis 2013; 19:1779-1794.
Table 1. Sensitivity and specificity of PPM-based selection methods.
| Characteristics of PPMs | PPM (2 HMX1-BS) | LS-PPM (1 HMX1-BS + 1 CAAG) | VLS-PPM (2 CAAG) |
|---|---|---|---|
| Predicted targets in the (-)-training set (%) | 0.5 | 14.7 | 59.3 |
| Predicted targets in the (+)-training set (%) | 10.0 | 20.0 | 63.3 |
| Fold-enrichment; P value (if <0.05) | 22.2; 0.0006 | 1.4 | 1.0 |
| Sensitivity | 10.0% (95% CI:2.2% - 26.6%) | 20.0% (95% CI:7.8% - 38.6%) | 63.3% (95% CI:43.9% - 80.1%) |
| Specificity | 99.6% (95%CI:99.2% - 99.8%) | 85.4% (95% CI:83.7% - 86.9%) | 40.8% (95% CI:38.6% - 42.9%) |