Figure 6 of Sheets, Mol Vis 2013; 19:1747-1759.


Figure 6. Microglial distribution in control and neuroprotectin D1-treated eyes. A: Lesion sectors from control and neuroprotectin D1 (NPD1)-treated eyes of the same animal highlight the differences in microglial distribution between treatments. B: The quantity of peripheral microglia per lesion sector was similar between treatments, but the spatial distribution was significantly different, with NPD1-treated microglia clustering 51% closer to the lesion perimeter than controls. The microglia count per sector is as follows: for Control, n=17; for NPD1, n=16; for total observations, n=3; and degrees of freedom = 31. The microglia distribution is as follows: for Control, n=503; for NPD1, n=462; for total observations, n=965; and degree of freedom = 933. C: An idealized schematic of a lesion sector illustrates a central lesion (black ring) with a ring for each treatment, representing the mean distance of microglia to the lesion perimeter.