Figure 5. Comparison of neovascularization in control and neuroprotectin D1-treated eyes. Choroidal neovascular lesions from control and neuroprotectin D1 (NPD1)-treated eyes of the same animal were visualized using isolectin B₄Griffonia simplicifolia (red) and CD11b (green). Control lesions demonstrate extensive ramification of both vascular endothelia (red) and monocytes (green). Neovasculature is drastically attenuated in NPD1-treated lesions. Quantitation of the lesion areas revealed a 56% reduction in neovascularization due to topical application of NPD1. For Control, n=26; for NPD1, n=24; for total observations, n=50; and degrees of freedom =48.