Figure 3. Multiple alignment of eight species of potassium channel, subfamily V, member 2 orthologs. The amino acid-sequence alignment is numbered in accordance with the Homo sapiens potassium channel, subfamily V, member 2 (KCNV2) sequence (ENSP00000371514). The positions of mutated residues, Arg27 (c.80 G>A, p.Arg27His), Arg177 (c.529 T>C, p.Cys177Arg), Arg206 (c.617 G>C, p.Arg206Pro), and Gly461 (c.1381 G>A, p.Gly461Arg), are highlighted. The alignment was performed with the Clustal Omega program, and the asterisk indicates a completely conserved residue.