Table 1 of Fernandez-Robredo, Mol Vis 2013; 19:153-165.


Table 1. Parameters from all the evaluated experiments.

Clinical signs score
Groups Conjuntival redness p Conjuntival edema p Lid redness p Lid Edema p Mucus secretion p
Vehicle 2.53±0.20 2.10±0.19 0.76±0.07 0.16±0.05 2.11±0.18
Azithromycin 1.88±0.19 <0.05 1.48±0.14 <0.05 0.40±0.07 <0.01 0.00±0.00 <0.05 1.43±0.19 <0.05
RNA expression
Groups COX-2 (RQ) p IL-6 (RQ) p MMP-2 (RQ) p MMP-9 (RQ) p TNF-α (RQ) p
Vehicle 1 1 1 1 1
Azithromycin 1.745 ns 1.038 ns 0.433 0.061 0.605 ns 0.828 ns
Protein analysis, macrophage infiltration and mucopolysacharide measurement
Groups IL-6 (ng/µl) p NF-κβ (%) p MMP-2 activity (%) p PAS staining (pixels) p CD 68 (cell number) p
Vehicle 2.03±0.45 100±3.4 100±6.2 429926±105314 134.5±29.6
Azithromycin 0.70±0.10 <0.05 84.18±3.3 <0.01 80.7±3.9 <0.05 154685±38542 <0.05 27.8±9.9 <0.05