Figure 3. Mapracorat inhibits interleukin-4 plus tumor necrosis factor-α-induced cytokines and intercellular adhesion molecule 1 in human conjunctival epithelial cells. Cells were treated with interleukin-4 (IL-4) plus tumor necrosis factor-α (TNF-α) in the presence of mapracorat or dexamethasone for 24 h. Cytokine/chemokine levels in the media and intercellular adhesion molecule 1 (ICAM-1) in the cell lysates were analyzed with Luminex. Gray bar represents control; black bar represents IL-4 plus TNF-α; black circles plus line represent dexamethasone; white circles plus line represent mapracorat. Lines are the result of a reparameterized four-parameter logistic equation fit to the data. Data are presented as mean ± standard error of the mean (SEM), n=3. * versus IL-4 plus TNF-α; p<0.05.