Table 4 of Pelikan, Mol Vis 2013; 19:1453-1470.

Table 4. Concentration of particular factors in tears during the secondary late conjunctival response (SLCR; n=13).

Factors Before the challenge After the challenge (h)
1/2 1 2 4 6 8 10 12 24 28
Histamine ng/ml
- SLCR <1.0 <1.0 3.3±0.5* 4.9±1.2* 3.5±0.7* <1.0 <1.0 <1.0 1.1±0.1 <1.0 <1.0
- PBS <1.0 <1.0 <1.0 <1.0 <1.0 <1.0 <1.0 <1.0 <1.0 <1.0 <1.0
ECP µg/l
- SLCR 2.3±0.1 3.0±0.7 8.8±1.3* 9.2±0.8* 12.5±0.7* 9.9±1.0* 9.3±1.4* 3.0±0.5 <2.0 <2.0 <2.0
- PBS 2.5±0.4 2.1±0.1 <2.0 <2.0 <2.0 <2.0 <2.0 <2.0 <2.0 <2.0 <2.0
LTB4 pg/ml
- SLCR <4.8 <4.8 5.8±1.3 9.4±0.7* 16.6±1.8* 14.9±1.1* 8.5±1.2* 6.1±0.7 <4.8 <4.8 5.2±0.3
- PBS <4.8 <4.8 <4.8 <4.8 <4.8 <4.8 <4.8 <4.8 5.1±0.2 <4.8 <4.8
LTC4 pg/ml
- SLCR 2.4±0.3 <2.1 <2.1 5.5±0.4* 6.0±1.2* 5.9±0.8* 2.2±0.1 2.6±0.3 <2.1 <2.1 <2.1
- PBS 2.2±0.1 <2.1 <2.1 <2.1 <2.1 2.3±0.2 <2.1 <2.1 <2.1 <2.1 <2.1
MPO ng/ml
- SLCR <25.0 <25.0 <25.0 <25.0 39.4±3.0* 48.1±2.6* 45.9±4.2* <25.0 <25.0 <25.0 <25.0
- PBS <25.0 <25.0 <25.0 <25.0 <25.0 <25.0 <25.0 <25.0 <25.0 <25.0 <25.0
IL-4 pg/ml
- SLCR 1.3±0.4 <0.7 <0.7 <0.7 6.2±1.3* 8.9±0.6* 5.1±0.2* <0.7 <0.7 <0.7 <0.7
- PBS 0.8±0.1 <0.7 <0.7 <0.7 <0.7 <0.7 1.0±0.3 <0.7 <0.7 <0.7 <0.7
IL-5 pg/ml
- SLCR 3.5±0.3 <3.2 <3.2 7.1±0.8* 6.5±0.6* 4.9±0.3 <3.2 <3.2 <3.2 <3.2 <3.2
- PBS <3.2 <3.2 <3.2 <3.2 <3.2 <3.2 <3.2 <3.2 <3.2 <3.2 <3.2

SLCR=Secondary late conjunctival response; PBS=Phosphate-buffered saline; Significance with respect to the baseline (before the challenge): *=p<0.05

Pelikan, Mol Vis 2013; 19:1453-1470. http://www.molvis.org/molvis/v19/1453

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