Table 2 of
Sharif, Mol Vis 2013; 19:1356-1370. Table 2 of
Sharif, Mol Vis 2013; 19:1356-1370.
Table 2. Agonist potencies of BK and related peptides and other compounds in production and release of total PGs in primary h-CM cells and in CHO-B2 cells
| Compound | Total PGs Production in h-CM cells (EC50, nM) | Total PGs production in CHO-B2 cells (EC50, pM) |
|---|---|---|
| BK | 8.6±2.4 | 26.3±6.6 |
| Hyp3-BK | 10.9±6.1 | 68.3±36.7 |
| Lys-BK | 13.1±4.9 | 66.3±52.2 |
| Met-Lys-BK | 23.3±9.5 | 104.0±11.4 |
| RMP-7 | 24.5±5.5 | 31.9±9.2 |
| Des-Arg9-BK | >1,000 | >100,000 |
| Sar-[D-Phe9 ]-Des-Arg9-BK | >1,000 | >1,000 |
| HOE-140 | >10,000 | >10,000 |
| (R)-WIN-64338 | >10,000 | >10,000 |
| (S)-WIN-64338 | >10,000 | >10,000 |