Figure 5. Effect of small interfering RNA–targeting tissue factor–2 on tube formation. Endothelial cell network formation was assessed using a Matrigel assay. A: Representative photographs of each group are shown (bar=500 μm). B: Small interfering RNA–targeting tissue factor (TF-siRNA)-2 and vascular endothelial growth factor (VEGF)-siRNA decreased the total number of branching points compared with the blank control (*p<0.001). Data are shown as mean±standard deviation (SD) from three independent experiments.