Table 3 of
Yazar, Mol Vis 2013; 19:1238-1246. Table 3 of
Yazar, Mol Vis 2013; 19:1238-1246.
Table 3. Strongest associated, genotyped single nucleotide polymorphisms (SNPs) for corneal astigmatism.
| SNP | CHR | bp | Allele | Raine (n=1013) | TEST/BATS (n=1771) | P value | Meta-analysis | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Effect | SEM | P value | Effect | SEM | Beta | SEM | P value | |||||
| rs1151008 | 12 | 31,988,627 | G | −0.138 | 0.046 | 3.07×10−3 | −0.15 | 0.038 | 7.50×10−5 | −0.144 | 0.03 | 1.37×10−6 |
| rs1164064 | 3 | 1.11E+08 | A | 0.212 | 0.043 | 9.91×10−7 | 0.065 | 0.037 | 7.50×10−2 | 0.134 | 0.028 | 1.86×10−6 |
| rs11841001 | 13 | 75,147,104 | A | 0.185 | 0.072 | 1.10×10−2 | 0.195 | 0.057 | 6.30×10−4 | 0.208 | 0.045 | 4.31×10−6 |
| rs7651778 | 3 | 1.58E+08 | C | 0.096 | 0.043 | 2.64×10−2 | 0.139 | 0.036 | 9.30×10−5 | 0.126 | 0.028 | 4.76×10−6 |
| rs11859036 | 16 | 78,863,052 | A | 0.145 | 0.043 | 8.74×10−4 | 0.107 | 0.037 | 3.60×10−3 | 0.128 | 0.029 | 7.03×10−6 |
| rs438465 | 6 | 1.7E+08 | C | −0.211 | 0.058 | 2.70×10−4 | −0.143 | 0.051 | 5.50×10−3 | −0.173 | 0.039 | 7.22×10−6 |
| rs979976 | 2 | 1.37E+08 | A | 0.163 | 0.047 | 4.81×10−4 | 0.102 | 0.038 | 7.20×10−3 | 0.134 | 0.03 | 7.52×10−6 |
| rs4805442 | 19 | 34,780,233 | A | −0.192 | 0.06 | 1.48×10−3 | −0.141 | 0.05 | 4.40×10−3 | −0.168 | 0.038 | 1.18×10−5 |
| rs10079889 | 5 | 33,011,247 | A | 0.165 | 0.052 | 1.50×10−3 | 0.124 | 0.043 | 4.30×10−3 | 0.145 | 0.033 | 1.38×10−5 |
| rs2116538 | 2 | 1.37E+08 | A | −0.162 | 0.052 | 1.92×10−3 | −0.135 | 0.044 | 2.10×10−3 | −0.146 | 0.034 | 1.63×10−5 |