Figure 3. Details of local packing changes caused by replacing D by G in position 26 of the molecule. Molecular modeling of wild-type and D26G, using the methods described in the Methods section. A: The interaction between D26 and R84 is shown. The numbers shown in the figure are in Ǻ units. B: The effect of replacing D26 by G is shown. C: The two structures (mutant in brown and WT in green) are overlain. Panel D shows how R84 in the mutant, having lost contact with D26, might enter into a long distance contact with D153 in the C-terminal domain.