Table 5 of
Huang, Mol Vis 2013; 19:1211-1221. Table 5 of
Huang, Mol Vis 2013; 19:1211-1221.
Table 5. Results of meta-analysis of the association between rs2010963 polymorphism of VEGF-A gene and AMD risk.
| Genotype contrast | Na | Cases/ Controls | OR (95% CI) | Significance (Z test)b | Heterogeneity (Q test) | |||
|---|---|---|---|---|---|---|---|---|
| Z | P | Q | I2 (%) | P | ||||
| overall | 3 | 614/454 | ||||||
| C versus G | 0.93 (0.77–1.12) | 0.7 | 0.48 | 1.77 | 0 | 0.41 | ||
| CC versus GG | 0.86 (0.56–1.32) | 0.69 | 0.49 | 3.83 | 47.8 | 0.14 | ||
| GC versus GG | 0.88 (0.66–1.17) | 0.87 | 0.38 | 1.28 | 0 | 0.52 | ||
| GC versus CC | 1.02 (0.49–2.15) | 0.07 | 0.94 | 6.07 | 67.1 | 0.04 | ||
| (GC+CC) versus GG | 0.90 (0.68–1.18) | 0.72 | 0.47 | 1.14 | 0 | 0.56 | ||
| CC versus (GG+CG) | 0.96 (0.49–1.89) | 0.1 | 0.91 | 5.48 | 63.5 | 0.06 | ||
| (GG+CC) versus GC | 1.05 (0.81–1.35) | 0.38 | 0.7 | 3.28 | 39.1 | 0.19 | ||
| wet AMD | 3 | 422/454 | ||||||
| C versus G | 0.90 (0.73–1.11) | 0.94 | 0.34 | 0.09 | 0 | 0.95 | ||
| CC versus GG | 0.81 (0.49–1.32) | 0.83 | 0.4 | 0.71 | 0 | 0.69 | ||
| GC versus GG | 0.85 (0.62–1.17) | 0.98 | 0.32 | 1.42 | 0 | 0.49 | ||
| GC versus CC | 0.95 (0.61–1.48) | 0.22 | 0.82 | 3.7 | 46 | 0.15 | ||
| (GC+CC) versus GG | 0.85 (0.63–1.16) | 0.99 | 0.32 | 0.56 | 0 | 0.75 | ||
| CC versus (GG+CG) | 0.88 (0.58–1.35) | 0.54 | 0.58 | 2.68 | 25.4 | 0.26 | ||
| (GG+CC) versus GC | 1.08 (0.81–1.43) | 0.56 | 0.57 | 3.7 | 46 | 0.15 | ||