Table 3 of
Tilleul, Mol Vis 2013; 19:1132-1140. Table 3 of
Tilleul, Mol Vis 2013; 19:1132-1140.
Table 3. Genetic characteristics of the population.
| Polymorphisms | Controls | Cases | p | corrected p† |
|---|---|---|---|---|
| n | 559 | 1224 | ||
| CFH | ||||
| TT, n(%) | 209 (37.7%) | 266 (21.8%) | <0.0001 | |
| CT | 268 (48.3%) | 612 (50.1%) | ||
| CC | 78 (14.0%) | 344 (28.1%) | ||
| ARMS2 | ||||
| GG | 330 (60.2%) | 373 (30.6%) | <0.0001 | |
| GT | 192 (35.1%) | 572 (46.9%) | ||
| TT | 26 (4.7%) | 274 (22.5%) | ||
| 4917 | ||||
| A | 509 (91.5%) | 1103 (90.1%) | 0.34 | 1 |
| G | 47 (8.5%) | 121 (9.9%) | ||
| 11812 | ||||
| A | 450 (92.8%) | 1058 (91.8%) | 0.52 | 1 |
| G | 35 (7.2%) | 94 (8.2%) | ||
| T2 (4917G11812G) | 34 (7.1%) | 94 (8.2%) | 0.45 | 1 |
| “Not T2” (4917A11812A or 4917G11812A) | 448 (92.9%) | 1058 (91.8%) | ||
| 14470 | ||||
| T | 528 (95.2%) | 1129 (97.7%) | 0.02* | 0.22 |
| C | 18 (3.2%) | 19 (1.6%) | ||
| A | 9 (1.6%) | 8 (0.7%) | ||
| C or A | 27 (4.9%) | 27 (2.3%) | 0.006 | 0.07 |
| G11778A | ||||
| G | 484 (100%) | 1139 (100%) | ||
| A11914G | ||||
| G | 478 (97.0%) | 1129 (98.2%) | 0.12 | 1 |
| A | 15 (3.0%) | 21 (1.8%) | ||
| G12007A | ||||
| G | 487 (98.4%) | 1128 (99.1%) | 0.19 | 1 |
| A | 8 (1.6%) | 10 (0.9%) | ||
| T14167C | ||||
| C | 507 (90.7%) | 1124 (98.8%) | 0.13 | 1 |
| T | 52 (9.3%) | 87 (7.2%) | ||
| T14110C | ||||
| T | 556 (99.6%) | 1200 (99.9%) | 0.24* | 1.00* |
| C | 2 (0.4%) | 1 (0.1%) | ||
| T14180C | ||||
| C | 558 (99.2%) | 1199 (99.4%) | 0.45* | 1.00* |
| T | 1 (0.2%) | 7 (0.6%) | ||
| T14182C | ||||
| T | 542 (97.0%) | 1165 (96.4%) | 0.58 | 1 |
| C | 17 (3.0%) | 43 (3.6%) | ||
| T14212C | ||||
| T | 556 (99.5%) | 1206 (99.5%) | 1.00* | 1.00* |
| C | 3 (0.5%) | 6 (0.5%) | ||
| G14364A | ||||
| G | 553 (99.1%) | 1174 (99.2%) | 1.00* | 1.00* |
| A | 5 (0.9%) | 10 (0.8%) |