Figure 5. The inhibition of CD26 activity partially attenuates the imidapril-induced decrease in the choroidal neovascularization lesion volume. Isolectin B4-stained endothelial cells in choroidal flatmounts 14 days following laser injury from vehicle-treated (A), imidapril-treated (B), diprotin-A-treated (C), and imidapril plus diprotin-A-treated (D) mice are presented. The newly formed blood vessels that make up the choroidal neovascularization (CNV) were stained by isolectin-B4 immunohistochemistry and imaged by confocal microscopy, to reveal the size of the CNV lesion. The results of the quantitative analysis are illustrated in (E). The values are expressed as the mean±standard deviation (n=8). The asterisk (*) indicates p<0.05. Dip-A represents diprotin-A. The scale bar represents 50 μm.