Figure 2. Imidapril elevates plasma stromal-derived factor-1 levels and the number of circulating endothelial precursor cells. Stromal-derived factor (SDF)-1 protein expression in the bone marrow supernatant (A) and the plasma (B) was determined using ELISA 0, 3, 7, and 14 days following laser-induced choroidal neovascularization (CNV). C: Representative fluorescence-activated cell sorting (FACS) data, based on which the CD34⁺/ vascular endothelial growth factor receptor 2 (VEGFR2)⁺ cells within the nucleated cell fraction of the peripheral blood from the different treatment groups were determined to be endothelial precursor cells (EPCs), are shown. D: The number of EPCs in the peripheral blood was determined using flow cytometry 12 days following laser-induced CNV. The values are expressed as the mean±standard deviation (n=5). The asterisk (*) indicates p<0.05. Dip-A represents diprotin-A.