Figure 7. Increased O-GlcNAc modification by high glucose or OGA inhibitors has a negative effect on retinal pericyte (PC) migration.
A: Cell migration was determined by scratch wounding of PC monolayers, and wound closure at 37 °C was monitored by photography.
A representative experiment is shown here. B: The quantitative assessment of the wound closure (**p<0.01, ***p<0.001, and ****p<0.0001; n=3).