Table 2 of Chiras, Mol Vis 2013; 19:1006-1016.

Table 2. Distribution of LOXL1 sequence variants in XFG, XFS, POAG patients and controls.

G153D n Alleles P value Genotypes P value† OR† (95%CI)
A G AA GA GG
XFG 71 19 123 0.002* 0 19 52 0.002* 2.794
0.13 0.87 0 0.27 0.73 (1.445–5.401)
XFS 53 17 89 0.032* 0 17 36 0.039* 2.162
0.16 0.84 0 0.32 0.68 (1.073–4.357)
POAG 43 16 70 >0.05 0 16 27 >0.05
0.19 0.81 0 0.37 0.63
Controls 97 53 141 4 45 48
0.27 0.73 0.04 0.46 0.49
R141L n T G P value TT GT GG P value† OR† (95%CI)
XFG 70 15 125 <0.001* 1 13 56 <0.001* 3.592
0.11 0.89 0.01 0.19 0.8 (1.760–7.329)
XFS 54 23 85 0.399 2 19 33 0.39 1.411
0.21 0.79 0.04 0.35 0.61 (0.713–2.791)
POAG 43 24 62 >0.05 4 16 23 >0.05
0.28 0.72 0.09 0.37 0.53
Controls 93 49 137 5 39 49
0.26 0.74 0.05 0.42 0.53

P values and OR are calculated when compared to controls. Asterisks (*) denote statistical significance. The daggers (†) indicate that the p values and OR ratios are derived from the comparison of the specific risk GG genotype versus all of the others.

Chiras, Mol Vis 2013; 19:1006-1016. http://www.molvis.org/molvis/v19/1006

©2013 Molecular Vision http://www.molvis.org/molvis/

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