Table 3 of Chen, Mol Vis 2012; 18:864-873.

Table 3. HIF-1α shRNA on corneal NV after 10 days of CL wear (mean±SD).

    Neovascularization score*  
Groups Number of eyes Maximum Minimum Mean p (versus control)
Normal 10 0 0 0 －
Control 10 5.49 1.81 3.59±1.1 －
Saline 10 5.20 2.61 4.05±0.75 0.141
Vehicle-RNAi 10 5.11 2.01 3.64±1.02 0.867
HIF-1αRNAi-A 10 2.83 0 1.13±0.96 0.000

Neovascularization was scored according to the distance from the limbus to the farthest end of the new vesicles: 0 (no visible vessels in cornea), +1.5 (1/4 distance to center), +2 (1/3 distance to center), +3 (1/2 distance to center), +4 (2/3 distance to center), +4.5 (3/4 distance to center) and +6 (vessels reach center).

Chen, Mol Vis 2012; 18:864-873. http://www.molvis.org/molvis/v18/a91

©2012 Molecular Vision http://www.molvis.org/molvis/

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